CAREER NETWORK World's one of the largest Research Career Network Benefits Academic & Industry jobs Project funding Visiting faculty positions Visiting scientist positions Invited talks and more... Register FREE Chemical Sensors 2011, 1: 15 Research Article Multi-walled carbon nanotube modified glassy carbon sensor for the determination of artesunate in bulk form and pharmaceuticals formulation Rajeev Jain, Vikas School of Studies in Chemistry, Jiwaji University, Gwalior – 474011, India Abstract The electroanalytical behaviour of artesunate (ART) in phosphate buffer of pH 3.51 at a multi-walled carbon nanotubes modified glassy electrode (MWCNTs/GC) has been investigated using squarewave, differential pulse voltammetry (DPV) and cyclic voltammetry (CV) techniques. Cathodic peak of artesunate is greatly improved at MWCNTs modified GC electrode (GCE) as compared with the bare GC electrode showing excellent electrocatalytic activity towards artesunate reduction. The peak current showed a linear dependence with the drug concentration over the range 2.0 to 20 µgmL-1. The calculated limits of detection (LOD) and limits of quantification (LOQ) are 2.49 ngmL-1 and 8.27 ngmL-1 by SWV and 54 ngmL-1 and 182 ngmL-1 by DPV respectively. The method was successfully applied for artesunate determination in bulk form and pharmaceutical formulation. Keywords Artesunate; Multi-walled Carbon Nanotube Modified Glassy Electrode; Pharmaceuticals Formulation; Sensor; Cetyltrimethylammonium Bromide